Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 199 entries
Sorted by: Best Match Show Resources per page
Editorial: Global Trends for Nanotechnological Approaches in Various Health Issues - Part 1.

Current drug metabolism

Kamal MA.
PMID: 26321194
Curr Drug Metab. 2015;16(5):334-5. doi: 10.2174/1389200216999150831130429.

No abstract available.

The recent development of nanoparticles for brain tumor targeting delivery.

Current drug metabolism

Shevtsov MA.
PMID: 27316690
Curr Drug Metab. 2016 Jun 15; Epub 2016 Jun 15.

Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted a lot of interest due to their widespread diagnostic and therapeutic applications in neuro-oncology. Functinalization of the particles surface with targeting molecules that recognize tumor receptors might be exploited for the specific...

Current drug metabolism.

Current drug metabolism

Huang CM.
PMID: 19149507
Curr Drug Metab. 2009 Jan;10(1):1. doi: 10.2174/138920009787048400.

No abstract available.

Letter to the Editor on "A System Pharmacology Study for Deciphering Anti Depression Activity of Nardostachys jatamansi".

Current drug metabolism

Sadri A.
PMID: 30947666
Curr Drug Metab. 2019;20(5):411. doi: 10.2174/1389200220666190402125932.

This letter is with reference to a recent article published in Current Drug Metabolism; A System Pharmacology Study for Deciphering Anti Depression Activity of Nardostachys jatamansi. Unfortunately, there is a major error in the "material and method" section of...

Inhibition of Efflux Pumps by Monoterpene (α-pinene) and Impact on .

Current drug metabolism

Freitas PR, de Araújo ACJ, Barbosa CR, Muniz DF, Tintino SR, Ribeiro-Filho J, Siqueira Júnior JP, Filho JMB, de Sousa GR, Coutinho HDM.
PMID: 32748743
Curr Drug Metab. 2021;22(2):123-126. doi: 10.2174/1389200221999200730212721.

INTRODUCTION: Infectious diseases have been responsible for an increasing number of deaths worldwide. Staphylococcus aureus has been recognized as one of the most notable causative agents of severe infections, while efflux pump (EP) expression is one of the main...

Applications of Machine Learning in Drug Target Discovery.

Current drug metabolism

Gao D, Chen Q, Zeng Y, Jiang M, Zhang Y.
PMID: 32723266
Curr Drug Metab. 2020;21(10):790-803. doi: 10.2174/1567201817999200728142023.

Drug target discovery is a critical step in drug development. It is the basis of modern drug development because it determines the target molecules related to specific diseases in advance. Predicting drug targets by computational methods saves a great...

Exosomes as Targeted Drug Delivery Vehicles: Perspectives and Challenges.

Current drug metabolism

Liu D, Li X.
PMID: 32614741
Curr Drug Metab. 2020;21(5):329. doi: 10.2174/138920022105200701160418.

No abstract available.

UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples.

Current drug metabolism

Chen WY, Liang GY, Zheng ZL, Wu YS, Xu FF, Liu B, Guo DA.
PMID: 33605854
Curr Drug Metab. 2021;22(6):491-499. doi: 10.2174/1389200222666210219123846.

BACKGROUND: Caesalpinia sappan L. is a traditional medicinal plant that is used to promote blood circulation and treat stroke in China. Protosappanin B (PTB) is a unique homoisoflavone compound isolated from Sappan Lignum (the heartwood of Caesalpinia sappan L)....

Oxypeucedanin is a mechanism-based inactivator of CYP2B6 and CYP2D6.

Current drug metabolism

Zhang K, Li Y, Fu Y, Cui T, Wang Q, Mao X, Peng Y, Zheng J.
PMID: 34191696
Curr Drug Metab. 2021 Jun 29; doi: 10.2174/1389200222666210629114830. Epub 2021 Jun 29.

BACKGROUND: Herbal medicine Angelica dahurica is widely employed for the treatment of rheumatism and pain relief in China. Oxypeucedanin is a major component of the herb.OBJECTIVES: The objectives of this study are aimed at the investigation of mechanism-based inactivation...

Amino Acid and Biogenic Amine Adductions Derived from Reactive Metabolites.

Current drug metabolism

Zhang Z, Peng Y, Zheng J.
PMID: 34915832
Curr Drug Metab. 2021;22(14):1076-1086. doi: 10.2174/1389200223666211216143617.

Reactive metabolites (RMs) are products generated from the metabolism of endogenous and exogenous substances. RMs are characterized as electrophilic species chemically reactive to nucleophiles. Those nucleophilic species may be nitrogen-containing bio-molecules, including macro-biomolecules, such as protein and DNA, and...

Alternative Drugs for Bacterial Resistance Control: Synergism through Resistance Inhibitors-Part II.

Current drug metabolism

Relison S, Pereira PS.
PMID: 33783342
Curr Drug Metab. 2021;22(2):108-109. doi: 10.2174/138920022202210302105958.

No abstract available.

Clopidogrel-Herb Interactions: A Pharmacokinetic and Pharmacodynamic Assessment in a Rat Model.

Current drug metabolism

Alkharfy K, Jan B, Alotaibi K, Alotaibi A, Alqahtani S, Raish M, Ahmad A.
PMID: 34719359
Curr Drug Metab. 2021 Oct 29; doi: 10.2174/1389200222666211029152151. Epub 2021 Oct 29.

BACKGROUND: Herbs usually contain a mixture of biologically active constituents, which can interact with numerous prescribed drugs and alter their safety profiles.OBJECTIVE: The current investigation was aimed to evaluate the effect of commonly used herbal products, including black seed...

Showing 1 to 12 of 199 entries